Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611102 | 0.89 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL4887109 | 0.89 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL11577551 | 0.83 | KDM4E (0.45) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL30127786 | 0.82 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL28275474 | 0.82 | KDM4E (0.47) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL250349 | 0.82 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL12869780 | 0.81 | KDM4E (0.46) | KDM4EHPGDALDH1A1HSD17B10GCGR | |
| SCHEMBL3724371 | 0.80 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL9664897 | 0.80 | KDM4E (0.51) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL29853841 | 0.79 | TSHR (0.45) | KDM4EALDH1A1HSD17B10GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1152362-A | — | — | None | — | — | JP | disclosed |
| JP-H01152362-A | ANALYSIS OF MONENSIN AND SODIUM MONENSIN BY FAST LIQUID CHROMATOGRAPHY | SHIMADZU CORP | 1989-06-14 | — | — | JP | disclosed |