Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.77 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 7/20 | 0.55 |
| ▸ | GART | P22102 | 2/20 | 0.51 |
| ▸ | ATIC | P31939 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289320 | 0.92 | TYMS (0.76) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL31121836 | 0.92 | TYMS (0.75) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL30749414 | 0.92 | AKR1B1 (0.77) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL30835527 | 0.92 | AKR1B1 (0.77) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL15864552 | 0.92 | AKR1B1 (0.77) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL28444343 | 0.91 | TYMS (0.76) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL29783453 | 0.91 | TYMS (0.76) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL29732719 | 0.90 | TYMS (0.75) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL27532324 | 0.90 | AKR1B1 (0.75) | TYMSAKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL30078340 | 0.90 | TYMS (0.82) | TYMSAKR1B1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12269859-B2 | Synthetic immune receptors and methods of use thereof | ANGELES THERAPEUTICS, INC. (US) | 2025-04-08 | — | — | US | claimed |
| US-20240390496-A1 | SINGLE-CHAIN AND MULTI-CHAIN SYNTHETIC ANTIGEN RECEPTORS FOR DIVERSE IMMUNE CELLS | CHAUDHARY, PREET M, DR. | 2024-11-28 | — | — | US | claimed |
| EP-4297769-A2 | SINGLE-CHAIN AND MULTI-CHAIN SYNTHETIC ANTIGEN RECEPTORS FOR DIVERSE IMMUNE CELLS | Chaudhary, Preet, M. (US) | 2024-01-03 | — | — | EP | claimed |
| CN-117202921-A | Single-and multi-chain synthetic antigen receptors for a variety of immune cells | 普里特·M·乔杜里 | 2023-12-08 | — | — | CN | claimed |
| WO-2022178367-A2 | SINGLE-CHAIN AND MULTI-CHAIN SYNTHETIC ANTIGEN RECEPTORS FOR DIVERSE IMMUNE CELLS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2022-08-25 | — | — | WO | claimed |
| US-20210309740-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | US | claimed |
| EP-3548055-A2 | SYNTHETIC IMMUNE RECEPTORS AND METHODS OF USE THEREOF | University of Southern California (US) | 2019-10-09 | — | — | EP | claimed |
| US-10189903-B2 | Bispecific chimeric antigen receptors and methods of use thereof to treat cancer | SEATTLE CHILDREN'S HOSPITAL (US) | 2019-01-29 | — | — | US | claimed |
| WO-2018102795-A2 | SYNTHETIC IMMUNE RECEPTORS AND METHODS OF USE THEREOF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-06-07 | — | — | WO | claimed |
| US-20170107285-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND ENCODING POLYNUCLEOTIDES THEREOF | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2017-04-20 | — | — | US | claimed |
| US-9447194-B2 | Bispecific chimeric antigen receptors and encoding polynucleotides thereof | SEATTLE CHILDREN'S HOSPITAL (US) | 2016-09-20 | — | — | US | claimed |
| US-20150038684-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2015-02-05 | — | — | US | claimed |
| EP-2814846-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF | Seattle Children's Hospital d/b/a Seattle Children's Research Institute (US) | 2014-12-24 | — | — | EP | claimed |
| WO-2013123061-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2013-08-22 | — | — | WO | claimed |
| WO-1989000603-A1 | A METHOD FOR THE EXPRESSION OF RECOMBINANT GENES UNDER STIMULATION FROM AN INDUCIVELY EXPRESSED ACTIVATOR PROTEIN | INTRACEL CORPORATION (BB) | 1989-01-26 | — | — | WO | claimed |
| EP-0299127-A1 | A method for the expression of recombinant genes under stimulation from an inducively expressed activator protein | IntraCel Corporation (BB) | 1989-01-18 | — | — | EP | claimed |
| EP-4735581-A2 | METHODS OF MAKING AND USING ENGINEERED IMMUNE CELLS | The Regents of University of California (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4646428-A1 | METHODS AND COMPOSITIONS FOR GENE TRANSDUCTION AND TO CONTROL THE ACTIVITY OF SYNTHETIC AND IMMUNE RECEPTORS | Angeles Therapeutics, Inc. (US) | 2025-11-12 | — | — | EP | disclosed |
| EP-2814846-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF | Seattle Children's Hospital d/b/a Seattle Children's Research Institute (US) | 2014-12-24 | — | — | EP | disclosed |
| WO-2013123061-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2013-08-22 | — | — | WO | disclosed |