SCHEMBL1053183

SCHEMBL1053183

CCCCCCCCc1ccc2c(c1C)C(=O)c1ccccc1C2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 10/20 0.56
CTSG P08311 5/20 0.56
PTPN1 P18031 1/20 0.49
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
LIPG Q9Y5X9 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
NPC1 O15118 1/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
HBB P68871 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
TYR P14679 1/20 0.42
NSD2 O96028 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30849360 0.87 ELANE (0.56) ELANECTSGPTPN1NR1H2NR1H3
SCHEMBL27631765 0.84 ELANE (0.59) ELANECTSGPTPN1NR1H2NR1H3
SCHEMBL1053180 0.83 ELANE (0.57) ELANECTSGPTPN1NR1H2NR1H3
SCHEMBL28036577 0.83 ELANE (0.57) ELANECTSGPTPN1NR1H2NR1H3
SCHEMBL10894897 0.82 ELANE (0.54) ELANECTSGPTPN1NR1H2NR1H3
SCHEMBL28056451 0.82 ELANE (0.58) ELANECTSGPTPN1NR1H2NR1H3
SCHEMBL8694531 0.82 ELANE (0.56) ELANECTSGPTPN1NR1H2NR1H3
SCHEMBL8694528 0.82 ELANE (0.56) ELANECTSGPTPN1NR1H2NR1H3
SCHEMBL28256775 0.82 ELANE (0.55) ELANECTSGPTPN1ALDH1A1MAPK1
SCHEMBL30389447 0.81 ELANE (0.56) ELANECTSGPTPN1NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110013865-A1 METHOD OF MANUFACTURING WIRING BOARD, METHOD OF MANUFACTURING OPTOELECTRIC COMPOSITE MEMBER, AND METHOD OF MANUFACTURING OPTOELECTRIC COMPOSITE BOARD HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-01-20 US disclosed
US-5629358-A Photocurable resin composition containing acrylate silane and epoxy silane and/or their hydrolysis products IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1997-05-13 US disclosed
EP-0549228-B1 Photocurable resin composition NAT STARCH CHEM INVEST (US) 1996-08-28 EP disclosed
EP-0549228-A2 Photocurable resin composition National Starch and Chemical Investment Holding Corporation (US) 1993-06-30 EP disclosed