Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MPL | P40238 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494755 | 0.95 | RARB (0.52) | RARBFAAHMPLHSD11B1HSD17B10 | |
| SCHEMBL9495358 | 0.94 | RARB (0.55) | RARBFAAHHSD11B1HSD17B10TSHR | |
| SCHEMBL18779835 | 0.94 | RARB (0.51) | RARBFAAHMPLHSD11B1HSD17B10 | |
| SCHEMBL15682610 | 0.94 | MPL (0.47) | RARBFAAHMPLHSD11B1HSD17B10 | |
| SCHEMBL9494695 | 0.94 | RARB (0.54) | RARBFAAHMPLHSD11B1HSD17B10 | |
| SCHEMBL9563690 | 0.92 | RARB (0.53) | RARBFAAHHSD11B1HSD17B10TSHR | |
| SCHEMBL9493991 | 0.92 | RARB (0.56) | RARBFAAHHSD11B1HSD17B10TSHR | |
| SCHEMBL9497269 | 0.92 | RARB (0.56) | RARBFAAHHSD11B1HSD17B10TSHR | |
| SCHEMBL9494324 | 0.92 | RARB (0.56) | RARBFAAHHSD11B1HSD17B10TSHR | |
| SCHEMBL9497740 | 0.92 | RARB (0.56) | RARBFAAHHSD11B1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989002425-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-03-23 | — | — | WO | disclosed |