SCHEMBL105342

SCHEMBL105342

CCC[O-].[Cs+]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6449280 0.89 TSHR (0.33)
SCHEMBL6449559 0.89 TSHR (0.33)
SCHEMBL1976924 0.89 TSHR (0.33)
SCHEMBL6449456 0.89 TSHR (0.33)
SCHEMBL3658482 0.89 TSHR (0.33)
SCHEMBL8916717 0.89 TSHR (0.33)
SCHEMBL6448290 0.89 TSHR (0.33)
SCHEMBL6943728 0.89 TSHR (0.33)
SCHEMBL15643453 0.89
SCHEMBL3458910 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108495847-B Process for producing 2-hydrazinobenzothiazole derivatives DIC株式会社 2022-07-01 CN claimed
CN-108409518-B Transition metal-free reductive cleavage of aromatic C-O, C-N and C-S bonds by reactive silanes 加州理工学院 2021-10-12 CN claimed
US-10968189-B2 Method for producing 2-hydrazinobenzothiazole derivative DIC CORPORATION (JP) 2021-04-06 US claimed
EP-2385054-B1 CEFDINIR ACID DOUBLE SALT AND ITS PREPARATION ZHEJIANG ADAMERCK BIOPHARMLABS INC (CN) 2013-10-02 EP claimed
US-8329895-B2 Cefdinir acid double salt and method for producing the same ZHEJIANG ADAMERCK BIOPHARMLABS INC. (CN) 2012-12-11 US claimed
EP-2385054-A1 CEFDINIR ACID DOUBLE SALT AND ITS PREPARATION Zhejiang Adamerck Biopharmlabs Inc. (CN) 2011-11-09 EP claimed
US-20110257388-A1 CEFDINIR ACID DOUBLE SALT AND METHOD FOR PRODUCING THE SAME ZHEJIANG ADAMERCK BIOPHARMLABS INC. (CN) 2011-10-20 US claimed
EP-1585714-B1 PROCESSES FOR THE PREPARATION OF HIGHER MOLECULAR WEIGHT KETONES EASTMAN CHEM CO (US) 2010-08-04 EP claimed
US-7071361-B2 Processes for the preparation of high molecular weight saturated ketones FASTMAN CHEMICAL COMPANY (US) 2006-07-04 US claimed
EP-1638913-A1 PROCESSES FOR PREPARING BETA-HYDROXY-KETONES AND ALPHA, BETA-UNSATURATED KETONES EASTMAN CHEMICAL COMPANY (US) 2006-03-29 EP claimed
EP-1616850-A1 Processes for the preparation of higher molecular weight saturated ketones in the presence of hydrogen, an hydrogenation catalyst, an hydroxide or alkoxide of alkaline or alkaline earth metal and less than 16% water. Eastman Chemical Company (US) 2006-01-18 EP claimed
US-20050288533-A1 PROCESSES FOR THE PREPARATION OF HIGHER MOLECULAR WEIGHT SATURATED KETONES EASTMAN CHEMICAL COMPANY 2005-12-29 US claimed
US-6979751-B2 Processes for the preparation of higher molecular weight ketones EASTMAN CHEMICAL COMPANY (US) 2005-12-27 US claimed
US-6960694-B2 Processes for preparing β-hydroxy-ketones and α,β-unsaturated ketones EASTMAN CHEMICAL COMPANY (US) 2005-11-01 US claimed
EP-1585714-A2 PROCESSES FOR THE PREPARATION OF HIGHER MOLECULAR WEIGHT KETONES EASTMAN CHEMICAL COMPANY (US) 2005-10-19 EP claimed
WO-2005028406-A2 PROCESSES FOR THE PREPARATION OF HIGHER MOLECULAR WEIGHT KETONES EASTMAN CHEMICAL COMPANY (US) 2005-03-31 WO claimed
WO-2005005361-A1 PROCESSES FOR PREPARING BETA-HYDROXY-KETONES AND ALPHA, BETA-UNSATURATED KETONES EASTMAN CHEMICAL COMPANY (US) 2005-01-20 WO claimed
US-20050004401-A1 Processes for preparing beta-hydroxy-ketones and alpha,beta-unsaturated ketones EASTMAN CHEMICAL COMPANY 2005-01-06 US claimed
US-20040122261-A1 Processes for the preparation of higher molecular weight ketones MCCUSKER-ORTH JENNIFER ELLEN (US) 2004-06-24 US claimed
US-12565493-B2 Method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one BASF SE (DE) 2026-03-03 US disclosed
WO-2025243002-A1 FLUORINATION PROCESS IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-11-27 WO disclosed
US-20240101547-A1 METHOD FOR PREPARING 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-OXO-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE BASF SE (DE) 2024-03-28 US disclosed
CN-116783169-A Process for preparing 2- [2- (2-chlorothiazol-5-yl) -2-oxoethyl ] sulfanyl-6-hydroxy-3-methyl-5-phenylpyrimidin-4-one 巴斯夫欧洲公司 2023-09-19 CN disclosed
US-11384093-B2 Process for preparing 2-exo-(2-Methylbenzyloxy)-1-methyl-4-isopropyl-7-oxabicyclo[2.2.1]heptane BASF Agro B.V. (NL) 2022-07-12 US disclosed
CN-108495847-B Process for producing 2-hydrazinobenzothiazole derivatives DIC株式会社 2022-07-01 CN disclosed
US-11192875-B2 Processes for preparing antiviral compounds GILEAD PHARMASSET LLC (US) 2021-12-07 US disclosed
US-10968189-B2 Method for producing 2-hydrazinobenzothiazole derivative DIC CORPORATION (JP) 2021-04-06 US disclosed
US-20200392100-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2020-12-17 US disclosed
CN-107922720-B Polycarbonate resin composition, method for producing same, and molded article 华东理工大学 2020-06-19 CN disclosed
US-20200165215-A1 METHOD FOR PRODUCING 2-HYDRAZINOBENZOTHIAZOLE DERIVATIVE DIC CORPORATION (JP) 2020-05-28 US disclosed
US-10584109-B2 Processes for preparing antiviral compounds Gillead Pharmasset LLC (US) 2020-03-10 US disclosed
US-20190263771-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2019-08-29 US disclosed
US-20180179175-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC 2018-06-28 US disclosed
US-9890134-B2 Processes for preparing antiviral compounds GILEAD PHARMASSET LLC (US) 2018-02-13 US disclosed
US-20170283390-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2017-10-05 US disclosed
EP-2241546-B1 PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-10-04 EP disclosed
US-9670187-B2 Processes for preparing antiviral compounds GILEAD PHARMASSET LLC (US) 2017-06-06 US disclosed
EP-3154984-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS Gilead Pharmasset LLC (US) 2017-04-19 EP disclosed
WO-2015191437-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC (US) 2015-12-17 WO disclosed
US-20150361073-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2015-12-17 US disclosed
US-20150344651-A1 PROCESS FOR MANUFACTURING GAS BARRIER FILM Konica Minolta, Inc. (JP) 2015-12-03 US disclosed
EP-2426098-B1 PROCESS FOR PRODUCING POLYHYDRIC PHENOL MITSUI CHEMICALS INC (JP) 2015-01-21 EP disclosed
US-20140113985-A1 POLYMER-DISPERSED POLYOL AND PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM ASAHI GLASS COMPANY, LIMITED (JP) 2014-04-24 US disclosed
US-8642668-B2 Polymer-dispersed polyol and process for producing flexible polyurethane foam ASAHI GLASS COMPANY, LIMITED (JP) 2014-02-04 US disclosed
US-8604253-B2 Method for producing polyhydric phenol MITSUI CHEMICALS, INC. (JP) 2013-12-10 US disclosed
US-20130274358-A1 METHOD FOR PRODUCING POLYETHER POLYOL AND METHOD FOR PRODUCING RIGID FOAM SYNTHETIC RESIN ASAHI GLASS COMPANY, LIMITED (JP) 2013-10-17 US disclosed
EP-2650318-A1 METHOD FOR PRODUCING POLYETHER POLYOL AND METHOD FOR PRODUCING RIGID FOAM SYNTHETIC RESIN Asahi Glass Company, Limited (JP) 2013-10-16 EP disclosed
EP-2385054-B1 CEFDINIR ACID DOUBLE SALT AND ITS PREPARATION ZHEJIANG ADAMERCK BIOPHARMLABS INC (CN) 2013-10-02 EP disclosed
EP-2554560-A1 FLEXIBLE POLYURETHANE FOAM AND PRODUCTION METHOD THEREFOR Asahi Glass Company, Limited (JP) 2013-02-06 EP disclosed
US-20130030068-A1 FLEXIBLE POLYURETHANE FOAM AND PROCESS FOR ITS PRODUCTION ASAHI GLASS COMPANY, LIMITED (JP) 2013-01-31 US disclosed
US-8329895-B2 Cefdinir acid double salt and method for producing the same ZHEJIANG ADAMERCK BIOPHARMLABS INC. (CN) 2012-12-11 US disclosed
US-8258349-B2 Process for production of benzaldehyde compound SUITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-04 US disclosed
US-20120202908-A1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM ASAHI GLASS COMPANY, LIMITED (JP) 2012-08-09 US disclosed
US-20120178840-A1 POLYMER-DISPERSED POLYOL AND PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM ASAHI GLASS COMPANY, LIMITED (JP) 2012-07-12 US disclosed
EP-2471826-A1 POLYMER-DISPERSED POLYOL AND METHOD FOR MANUFACTURING A SOFT POLYURETHANE FOAM Asahi Glass Company, Limited (JP) 2012-07-04 EP disclosed
EP-2471830-A1 PROCESS FOR PRODUCTION OF FLEXIBLE POLYURETHANE FOAM Asahi Glass Company, Limited (JP) 2012-07-04 EP disclosed
EP-2426098-A1 PROCESS FOR PRODUCING POLYHYDRIC PHENOL Mitsui Chemicals, Inc. (JP) 2012-03-07 EP disclosed
US-20120046498-A1 METHOD FOR PRODUCING POLYHYDRIC PHENOL MITSUI CHEMICALS, INC. (JP) 2012-02-23 US disclosed
EP-2385054-A1 CEFDINIR ACID DOUBLE SALT AND ITS PREPARATION Zhejiang Adamerck Biopharmlabs Inc. (CN) 2011-11-09 EP disclosed
US-20110257388-A1 CEFDINIR ACID DOUBLE SALT AND METHOD FOR PRODUCING THE SAME ZHEJIANG ADAMERCK BIOPHARMLABS INC. (CN) 2011-10-20 US disclosed
US-20100292513-A1 PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-18 US disclosed
EP-2241546-A1 PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-1585714-B1 PROCESSES FOR THE PREPARATION OF HIGHER MOLECULAR WEIGHT KETONES EASTMAN CHEM CO (US) 2010-08-04 EP disclosed
US-20100096768-A1 POLYMER-DISPERSED POLYOL AND PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM ASAHI GLASS COMPANY, LIMITED (JP) 2010-04-22 US disclosed
EP-2161289-A1 METHOD FOR PRODUCTION OF POLYMER-DISPERSED POLYOL, AND METHOD FOR PRODUCTION OF FLEXIBLE POLYURETHANE FOAM Asahi Glass Company, Limited (JP) 2010-03-10 EP disclosed
US-20090239964-A1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM ASAHI GLASS COMPANY, LIMITED (JP) 2009-09-24 US disclosed
EP-2067804-A1 METHOD FOR PRODUCING SOFT POLYURETHANE FOAM Asahi Glass Company, Limited (JP) 2009-06-10 EP disclosed
CN-100415794-C Polyurethane resins and process for production thereof ASAHI GLASS CO LTD (JP) 2008-09-03 CN disclosed
EP-1619212-B1 REACTIVE MODIFIER KANEKA CORP (JP) 2008-08-06 EP disclosed
US-7385006-B2 Reactive modifier KANEKA CORPORATION (JP) 2008-06-10 US disclosed
EP-1445283-B1 CURABLE RESIN COMPOSITION KANEKA CORP (JP) 2007-09-05 EP disclosed
EP-1806333-A1 A method for manufacturing dialkyl carbonate GENERAL ELECTRIC COMPANY (US) 2007-07-11 EP disclosed
EP-1299341-B1 A METHOD FOR MANUFACTURING DIALKYL CARBONATE GEN ELECTRIC (US) 2007-04-25 EP disclosed
US-7144953-B2 Material handling; radiation transparent; adhesives KANEKA CORPORATION (JP) 2006-12-05 US disclosed
US-20060199918-A1 Reactive modifier KANEKA CORPORATION (JP) 2006-09-07 US disclosed
CN-1816579-A Polyurethane resin and method for producing same ASAHI GLASS CO LTD (JP) 2006-08-09 CN disclosed
US-7071361-B2 Processes for the preparation of high molecular weight saturated ketones FASTMAN CHEMICAL COMPANY (US) 2006-07-04 US disclosed
US-20060122356-A1 Polyurethane resin and process for producing the same ASAHI GLASS COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1273605-B1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM ASAHI GLASS CO LTD (JP) 2006-06-07 EP disclosed
EP-1650239-A1 POLYURETHANE RESINS AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY LTD. (JP) 2006-04-26 EP disclosed
EP-1638913-A1 PROCESSES FOR PREPARING BETA-HYDROXY-KETONES AND ALPHA, BETA-UNSATURATED KETONES EASTMAN CHEMICAL COMPANY (US) 2006-03-29 EP disclosed
EP-1619212-A1 REACTIVE MODIFIER KANEKA CORPORATION (JP) 2006-01-25 EP disclosed
EP-1616850-A1 Processes for the preparation of higher molecular weight saturated ketones in the presence of hydrogen, an hydrogenation catalyst, an hydroxide or alkoxide of alkaline or alkaline earth metal and less than 16% water. Eastman Chemical Company (US) 2006-01-18 EP disclosed
US-20050288533-A1 PROCESSES FOR THE PREPARATION OF HIGHER MOLECULAR WEIGHT SATURATED KETONES EASTMAN CHEMICAL COMPANY 2005-12-29 US disclosed
US-6979751-B2 Processes for the preparation of higher molecular weight ketones EASTMAN CHEMICAL COMPANY (US) 2005-12-27 US disclosed
US-6960694-B2 Processes for preparing β-hydroxy-ketones and α,β-unsaturated ketones EASTMAN CHEMICAL COMPANY (US) 2005-11-01 US disclosed
EP-1585714-A2 PROCESSES FOR THE PREPARATION OF HIGHER MOLECULAR WEIGHT KETONES EASTMAN CHEMICAL COMPANY (US) 2005-10-19 EP disclosed
WO-2005028406-A2 PROCESSES FOR THE PREPARATION OF HIGHER MOLECULAR WEIGHT KETONES EASTMAN CHEMICAL COMPANY (US) 2005-03-31 WO disclosed
WO-2005005361-A1 PROCESSES FOR PREPARING BETA-HYDROXY-KETONES AND ALPHA, BETA-UNSATURATED KETONES EASTMAN CHEMICAL COMPANY (US) 2005-01-20 WO disclosed
US-20050004401-A1 Processes for preparing beta-hydroxy-ketones and alpha,beta-unsaturated ketones EASTMAN CHEMICAL COMPANY 2005-01-06 US disclosed
US-20050004327-A1 Material handling; radiation transparent; adhesives KANEKA CORPORATION (JP) 2005-01-06 US disclosed
EP-1445283-A1 CURABLE RESIN COMPOSITION KANEKA CORPORATION (JP) 2004-08-11 EP disclosed
US-20040122261-A1 Processes for the preparation of higher molecular weight ketones MCCUSKER-ORTH JENNIFER ELLEN (US) 2004-06-24 US disclosed
US-6653362-B2 Using as polyol component specified polyethers made using different catalysts including zinc hexacyanocobaltate and an alkali metal hydroxide, and an addition-condensation co-polyether; vibration absorption, low resilience: auto seat ASAHI GLASS COMPANY, LIMITED (JP) 2003-11-25 US disclosed
EP-1299341-A2 A METHOD FOR MANUFACTURING DIALKYL CARBONATE GENERAL ELECTRIC COMPANY (US) 2003-04-09 EP disclosed
US-20030045595-A1 Process for producing flexible polyurethane foam ASAHI GLASS COMPANY LIMITED (JP) 2003-03-06 US disclosed
EP-1273605-A1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM ASAHI GLASS COMPANY LTD. (JP) 2003-01-08 EP disclosed
US-6458914-B2 REACTING CARBON MONOXIDE, OXYGEN AND ALCOHOL IN THE PRESENCE OF A CATALYST PRODUCED BY REACTING TOGETHER AND INCLUDING A CUPRIC HALIDE AND AN ALKOXIDE COMPOUND OF A GROUP III THROUGH VII METAL; EFFICIENCY; ANTIFOULING AGENTS GENERAL ELECTRIC COMPANY 2002-10-01 US disclosed
EP-1189870-A1 METHOD FOR MANUFACTURING DIALKYL CARBONATE GENERAL ELECTRIC COMPANY (US) 2002-03-27 EP disclosed
US-20020007087-A1 Method for manufacturing dialkyl carbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-01-17 US disclosed
WO-2002000596-A2 A METHOD FOR MANUFACTURING DIALKYL CARBONATE GENERAL ELECTRIC COMPANY (US) 2002-01-03 WO disclosed
US-6258923-B1 REACTING CARBON MONOXIDE, OXYGEN AND ALCOHOL GENERAL ELECTRIC COMPANY 2001-07-10 US disclosed
WO-2000076950-A1 METHOD FOR MANUFACTURING DIALKYL CARBONATE GENERAL ELECTRIC COMPANY (US) 2000-12-21 WO disclosed
US-5308888-A Heat resistant, fire retardant resin HITACHI, LTD. (JP) 1994-05-03 US disclosed
EP-0444213-A1 HEXAFLUOROBUTADIENE PREPOLYMER, PRODUCTION THEREOF, POLYMERIZABLE COMPOSITION, AND LAMINATE HITACHI, LTD. (JP) 1991-09-04 EP disclosed
EP-0444213-A1 HEXAFLUOROBUTADIENE PREPOLYMER, PRODUCTION THEREOF, POLYMERIZABLE COMPOSITION, AND LAMINATE HITACHI, LTD. (JP) 1991-09-04 EP disclosed