Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537039 | 0.83 | POLB (0.57) | KMT2AALDH1A1MAPTLMNAGAA | |
| SCHEMBL21538582 | 0.82 | KMT2A (0.63) | KMT2AMMEALDH1A1MAPTCA12 | |
| SCHEMBL21538610 | 0.82 | KMT2A (0.63) | KMT2AMMEALDH1A1MAPTCA12 | |
| SCHEMBL8073195 | 0.82 | KMT2A (0.57) | KMT2AMMEALDH1A1MAPTGAA | |
| SCHEMBL12240252 | 0.81 | KMT2A (0.57) | KMT2AMMEALDH1A1MAPTGAA | |
| SCHEMBL8930750 | 0.81 | KMT2A (0.76) | KMT2AMMEALDH1A1MAPTCA12 | |
| SCHEMBL30476096 | 0.81 | KMT2A (0.57) | KMT2AMMEALDH1A1MAPTGAA | |
| SCHEMBL8760 | 0.78 | KMT2A (0.67) | KMT2AMMEALDH1A1MAPTCA12 | |
| SCHEMBL10031574 | 0.77 | MME (0.65) | KMT2AMMEALDH1A1MAPTLMNA | |
| SCHEMBL1516159 | 0.77 | MME (0.65) | KMT2AMMEALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801750-A | Process for the produciton of 2-chloroacetoacetic acid amides | LONZA LTD. (CH) | 1989-01-31 | — | — | US | disclosed |