Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | F3 | P13726 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535075 | 0.89 | PPM1B (0.41) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL10533539 | 0.83 | MAPT (0.40) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL880070 | 0.82 | MAPT (0.39) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL10290660 | 0.82 | MAPT (0.43) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL879910 | 0.80 | MAPT (0.42) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL29191208 | 0.78 | MAPT (0.40) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL849880 | 0.75 | POLB (0.41) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL2329373 | 0.74 | MAPT (0.44) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL879911 | 0.74 | KMT2A (0.39) | MAPTKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28822221 | 0.74 | MAPT (0.46) | MAPTKMT2ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989011496-A1 | SIDE-CHAIN POLYMERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-30 | — | — | WO | disclosed |