Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12456081 | 0.92 | CYP1A2 (0.67) | CYP1A2SMN1; SMN2GAAPDE4ACA12 | |
| SCHEMBL2538688 | 0.92 | CYP1A2 (0.72) | CYP1A2SMN1; SMN2GAAPDE4ACA12 | |
| SCHEMBL2534556 | 0.90 | CYP1A2 (0.70) | CYP1A2SMN1; SMN2GAAPDE4ACA12 | |
| SCHEMBL7887937 | 0.87 | SMN1; SMN2 (0.52) | CYP1A2SMN1; SMN2GAAPDE4ACA12 | |
| SCHEMBL8520095 | 0.84 | SMN1; SMN2 (0.65) | CYP1A2SMN1; SMN2GAAPDE4ACA12 | |
| SCHEMBL27917592 | 0.82 | SMN1; SMN2 (0.48) | CYP1A2SMN1; SMN2GAAPDE4ACA12 | |
| SCHEMBL1715467 | 0.81 | CYP1A2 (0.80) | CYP1A2SMN1; SMN2GAAPDE4ACA12 | |
| SCHEMBL2985757 | 0.79 | SMN1; SMN2 (0.75) | CYP1A2SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL21874406 | 0.78 | SMN1; SMN2 (0.73) | CYP1A2SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL13534110 | 0.78 | SMN1; SMN2 (0.73) | CYP1A2SMN1; SMN2GAAPDE4ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| US-4824477-A | Trifluoromethanesulfonanilide compounds and herbicidal compositions containing them | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0265540-A1 | Trifluoromethanesulfonanilide compounds and herbicidal compositions containing them | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-05-04 | — | — | EP | disclosed |
| US-4659371-A | NONPHYTOTOXIC TO COTTON | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-04-21 | — | — | US | disclosed |