SCHEMBL10539007

SCHEMBL10539007

CCCCCC(C)C(CC[C@H]1C(OC2CCCCO2)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TBXA2R P21731 7/20 0.44
ALDH1A1 P00352 5/20 0.44
LMNA P02545 4/20 0.44
PTGFR P43088 3/20 0.44
SLCO2A1 Q92959 2/20 0.44
PTGER1 P34995 2/20 0.44
PTGER3 P43115 2/20 0.44
PTGER4 P35408 1/20 0.44
PTGDR Q13258 1/20 0.44
HPGD P15428 2/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
HIF1A Q16665 1/20 0.43
ABCC4 O15439 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.39
PDE4D Q08499 2/20 0.39
PGR P06401 1/20 0.38
ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10540664 1.00 MEN1 (0.44) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL10536458 0.98 MEN1 (0.41) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL10538754 0.98 MEN1 (0.41) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL10537169 0.91 MEN1 (0.45) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL10536886 0.91 MEN1 (0.45) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL10536115 0.91 MEN1 (0.45) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL16468533 0.91 MEN1 (0.44) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL19847193 0.91 MEN1 (0.44) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL16466822 0.91 MEN1 (0.44) MEN1KMT2ATBXA2RALDH1A1LMNA
SCHEMBL10539802 0.89 PTGFR (0.46) MEN1KMT2ATBXA2RALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4888358-A 13,14-dihydroprostaglandin C-type derivatives SYNTEX (U.S.A.) INC. (US) 1989-12-19 US disclosed