Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.64 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636229 | 0.85 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10663420 | 0.85 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL10632764 | 0.84 | CYSLTR1 (0.70) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10655893 | 0.82 | CYSLTR1 (0.70) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9081303 | 0.82 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL10513942 | 0.82 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| Hydrochloric Acid SCHEMBL9447146 | 0.81 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10632386 | 0.81 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10635391 | 0.81 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8171622 | 0.81 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223368-A1 | Substituted naphthalene derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-27 | — | — | EP | claimed |
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| US-4732978-A | RESPIRATORY SYSTEM DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-03-22 | — | — | US | disclosed |
| US-4728668-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| US-4725619-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| EP-0223368-A1 | Substituted naphthalene derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-27 | — | — | EP | disclosed |
| US-4631287-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORP. (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |