Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12477096 | 0.89 | GAA (0.62) | GAANPSR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2010751 | 0.86 | GAA (0.59) | GAANPSR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2010507 | 0.86 | GAA (0.59) | GAANPSR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL16035326 | 0.85 | NPSR1 (0.66) | GAANPSR1ALDH1A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL11660184 | 0.84 | GAA (0.57) | GAANPSR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL3495434 | 0.83 | PLA2G4B (0.68) | GAANPSR1ALDH1A1MAPTHPGD | |
| SCHEMBL11109551 | 0.83 | MAPT (0.54) | GAAALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL707685 | 0.83 | GAA (0.64) | GAANPSR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL6941063 | 0.83 | GAA (0.64) | GAANPSR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11815554 | 0.83 | GAA (0.72) | GAANPSR1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33109-E | ANTIULCER, ANTIINFLAMMATORY | BIOREX LABORATORIES LIMITED (GB) | 1989-11-07 | — | — | US | disclosed |
| US-4656305-A | ANTIINFLAMMATORY AND ANTIULCER AGENTS; ANTIALLERGENS; ANALGESICS | BIOREX LABORATORIES, LIMITED (GB) | 1987-04-07 | — | — | US | disclosed |