Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 1.00 |
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 1.00 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.75 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.75 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021495 | 0.91 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL14021528 | 0.90 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL14021744 | 0.88 | CYSLTR1 (0.79) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL25244522 | 0.88 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL30443831 | 0.88 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8646512 | 0.88 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL30444024 | 0.86 | CYSLTR1 (0.77) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL25212445 | 0.86 | CYSLTR1 (0.77) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8649544 | 0.85 | FFAR1 (0.97) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL14021499 | 0.84 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |