Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354434 | 0.86 | CA1 (0.47) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL18797540 | 0.84 | NPC1 (0.42) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL25804814 | 0.84 | NPC1 (0.55) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL11576400 | 0.84 | CA1 (0.51) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL2308156 | 0.84 | CA1 (0.50) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL18821159 | 0.83 | HPGD (0.41) | CA1CA2CA9HDAC1NPC1 | |
| SCHEMBL15496681 | 0.81 | HDAC1 (0.49) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL11575326 | 0.81 | CA1 (0.45) | CA1CA2CA9HDAC1HDAC3 | |
| SCHEMBL23579625 | 0.80 | HDAC1 (0.51) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL30987572 | 0.80 | HDAC1 (0.51) | CA1CA2CA9HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801408-A | 3-AMINO-4-FLUORO-6-HALOPHENYLTHIOACETIC ACIDS, 5-SUBSTITUTED ACETANILIDES, HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0126419-B1 | 2-SUBSTITUTED PHENYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4709049-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | disclosed |
| US-4684397-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0126419-A1 | 2-Substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |