Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 9/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 8/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1054651 | 0.94 | F2R (0.59) | F2RCNR1TMEM97GRM5KMT2A | |
| SCHEMBL1050091 | 0.94 | F2R (0.53) | F2RCNR1TMEM97KMT2A | |
| SCHEMBL1054716 | 0.92 | F2R (0.49) | F2RCNR1TMEM97GRM5 | |
| SCHEMBL1053095 | 0.90 | F2R (0.46) | F2RCNR1TMEM97GRM5KMT2A | |
| SCHEMBL1055232 | 0.89 | F2R (0.66) | F2RCNR1TMEM97GRM5KMT2A | |
| SCHEMBL1051881 | 0.89 | F2R (0.51) | F2RCNR1TMEM97GRM5KMT2A | |
| SCHEMBL1055400 | 0.89 | F2R (0.52) | F2RCNR1TMEM97GRM5KMT2A | |
| SCHEMBL1050092 | 0.88 | F2R (0.60) | F2RCNR1TMEM97KMT2A | |
| SCHEMBL3722786 | 0.86 | F2R (0.67) | F2RCNR1TMEM97GRM5 | |
| SCHEMBL1054688 | 0.85 | F2R (0.48) | F2RCNR1TMEM97GRM5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084469-B2 | Substituted piperidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-27 | — | — | US | disclosed |
| US-20110021489-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021489-A1 | SUBSTITUTED PIPERIDINES | VHL, PIR, PIGO | F2R 1339/4885CNR1 460/4885TMEM97 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.