Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 6/20 | 0.63 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545898 | 0.83 | VHL (0.77) | VHLEGLN2P4HTMGAAMEN1 | |
| SCHEMBL10549972 | 0.82 | VHL (0.69) | VHLEGLN2P4HTMGAAMEN1 | |
| SCHEMBL3588060 | 0.82 | VHL (0.70) | VHLEGLN2P4HTMGAAMEN1 | |
| SCHEMBL10547680 | 0.80 | VHL (0.67) | VHLEGLN2P4HTMGAAMEN1 | |
| SCHEMBL10546531 | 0.80 | VHL (0.69) | VHLEGLN2CD274P4HTMGAA | |
| SCHEMBL8258776 | 0.79 | VHL (0.60) | VHLEGLN2P4HTMGAAMEN1 | |
| SCHEMBL10547972 | 0.78 | SLC11A2 (0.62) | VHLEGLN2CD274P4HTMGAA | |
| SCHEMBL563926 | 0.77 | VHL (0.66) | VHLEGLN2P4HTMGAANOX4 | |
| SCHEMBL3596862 | 0.77 | VHL (0.72) | VHLEGLN2P4HTMGAAMAPK1 | |
| SCHEMBL10547952 | 0.77 | VHL (0.64) | VHLEGLN2CD274P4HTMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806540-A | FUNGICIDES, PARASITICIDES, AND SLIMICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| US-4772608-A | FUNGICIDES, BACTERICIDES, SLIMICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |