Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 15/20 | 0.78 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.65 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.64 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.64 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.64 |
| ▸ | CDK2 | P24941 | 2/20 | 0.64 |
| ▸ | CDK9 | P50750 | 2/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.64 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.64 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.64 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13234628 | 0.87 | FYN (1.00) | FYNDYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL1051343 | 0.86 | FYN (0.72) | FYNMKNK1 | |
| SCHEMBL2942585 | 0.86 | FYN (0.72) | FYNMKNK1 | |
| SCHEMBL2943274 | 0.86 | FYN (0.72) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL1052447 | 0.85 | FYN (0.81) | FYNMKNK1 | |
| SCHEMBL1049257 | 0.84 | FYN (0.70) | FYNMKNK1 | |
| SCHEMBL2945964 | 0.84 | FYN (1.00) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL1049258 | 0.84 | FYN (0.83) | FYNMKNK1DYRK3DYRK1ADYRK2 | |
| SCHEMBL18613660 | 0.83 | FYN (1.00) | FYNMKNK1 | |
| SCHEMBL1056095 | 0.83 | FYN (0.81) | FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021513-A1 | MODULATORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE | BIOGEN IDEC MA INC. (US) | 2011-01-27 | — | — | US | claimed |
| US-20110021513-A1 | MODULATORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE | BIOGEN IDEC MA INC. (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021513-A1 | MODULATORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE | IRAK1, IRAK2, IRAK3 | FYN 666/4885MKNK1 105/4885DYRK3 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.