Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545086 | 0.92 | TTR (0.34) | TTRNR3C1PPARGLPAR1LPAR5 | |
| SCHEMBL10544842 | 0.91 | FDFT1 (0.33) | TTRNR3C1PPARGLPAR1LPAR5 | |
| SCHEMBL10546784 | 0.89 | FFAR1 (0.37) | TTRNR3C1FFAR1PPARGLPAR1 | |
| SCHEMBL10544498 | 0.89 | PPARG (0.32) | TTRNR3C1PPARGLPAR1LPAR5 | |
| SCHEMBL9030662 | 0.87 | TTR (0.38) | TTRLPAR1LPAR5KCNH2 | |
| SCHEMBL10543447 | 0.87 | FFAR1 (0.35) | TTRNR3C1FFAR1PPARGLPAR1 | |
| SCHEMBL10545998 | 0.86 | TTR (0.34) | TTRNR3C1LPAR1LPAR5 | |
| SCHEMBL10547396 | 0.86 | MAPT (0.36) | TTRPPARG | |
| SCHEMBL10543680 | 0.86 | TTR (0.36) | TTRNR3C1PPARGLPAR1LPAR5 | |
| SCHEMBL10546952 | 0.85 | TTR (0.38) | TTRNR3C1FFAR1LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |