Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 10/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGIS | Q16647 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3092746 | 0.85 | TBXA2R (0.79) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL12675359 | 0.85 | TBXA2R (0.79) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL1897185 | 0.85 | TBXA2R (0.79) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL13378988 | 0.85 | TBXA2R (0.79) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL15301375 | 0.85 | TBXA2R (0.79) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL24441305 | 0.84 | TBXA2R (1.00) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL1900728 | 0.84 | TBXA2R (1.00) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL2939361 | 0.84 | TBXA2R (1.00) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL7081320 | 0.84 | TBXA2R (1.00) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL3112563 | 0.84 | TBXA2R (1.00) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246002-A2 | Alkenamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-11-19 | — | — | EP | claimed |
| US-4845120-A | THROMBOXANE ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-04 | — | — | US | disclosed |
| EP-0246002-A2 | Alkenamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-11-19 | — | — | EP | disclosed |