Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL833023 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL10296745 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL15319069 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL9292756 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL247526 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL596019 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL1065045 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL1302577 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL10869333 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 | |
| SCHEMBL19951524 | 0.92 | TSHR (0.41) | CNR2CNR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839383-A | REPELLING, ATTRACTING PHEROMONES | CELAMERCK GMBH & CO. (DE) | 1989-06-13 | — | — | US | disclosed |