Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345135 | 0.88 | GSK3B (0.50) | GSK3B | |
| SCHEMBL10546585 | 0.86 | GSK3B (0.55) | GSK3BMEN1KMT2A | |
| SCHEMBL9757352 | 0.84 | GSK3B (0.58) | GSK3BMEN1KMT2ATOP2ATOP2B | |
| SCHEMBL9501093 | 0.84 | GSK3B (0.54) | GSK3BTOP2ATOP2B | |
| SCHEMBL10576254 | 0.83 | GSK3B (0.54) | GSK3BMEN1KMT2A | |
| SCHEMBL10576261 | 0.83 | GSK3B (0.54) | GSK3BMEN1KMT2A | |
| SCHEMBL10576245 | 0.83 | GSK3B (0.54) | GSK3BMEN1KMT2A | |
| SCHEMBL9688639 | 0.81 | GSK3B (0.60) | GSK3BMEN1KMT2ATOP2ATOP2B | |
| SCHEMBL5704357 | 0.80 | GSK3B (0.48) | GSK3B | |
| SCHEMBL9268466 | 0.80 | STAT3 (0.43) | GSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886810-A | ANTIBACTERIAL | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| US-4795751-A | 5-substituted-6,8-difluoroquinolines useful as antibacterial agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |