⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12314824 | 0.92 | CYP2D6 (0.45) | — | |
| SCHEMBL12314822 | 0.88 | CYP2D6 (0.47) | — | |
| SCHEMBL26234244 | 0.80 | CYP2D6 (0.39) | — | |
| SCHEMBL13249198 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL10060803 | 0.79 | — | — | |
| SCHEMBL4167824 | 0.79 | CYP2D6 (0.50) | — | |
| SCHEMBL20147019 | 0.77 | — | — | |
| SCHEMBL24723754 | 0.75 | CYP2D6 (0.37) | — | |
| SCHEMBL20957529 | 0.75 | — | — | |
| SCHEMBL4468978 | 0.75 | CYP2D6 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820846-B1 | COMPOSITION FOR INHIBITING MONOMER POLYMERIZATION COMPRISING A NITROXIDE INHIBITOR, A QUINONE METHIDE RETARDER AND AN AMINE STABILIZER | ECOLAB USA INC (US) | 2024-01-03 | — | — | EP | disclosed |
| WO-2023212057-A1 | COMPOSITIONS OF KINETIC NANOPARTICLES CONTAINING NUCLEIC ACIDS, POLYCATIONS AND LIPIDS | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20230338415-A1 | SUBSTITUTED PHENYL BORONIC ACID CONTAINING POLYMERS AND METHODS OF USE | GLYSCEND, INC. | 2023-10-26 | — | — | US | disclosed |
| WO-2023154818-A1 | MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS | MODERNATX, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
| WO-2023093845-A1 | CHIMERIC COMPOUND FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR PROTEIN, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2023-06-01 | — | — | WO | disclosed |
| WO-2023077150-A1 | POLYMERS AND NANOPARTICLES FOR INTRAMUSCULAR NUCLEIC ACID DELIVERY | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023069549-A1 | METHODS AND COMPOSITIONS COMPRISING PEPTIDOMIMITICS FOR TREATING, PREVENTING, INHIBITING, AMELIORATING OR DELAYING THE ONSET OF OPHTHALMIC CONDITIONS | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-11576928-B2 | Substituted phenyl boronic acid containing polymers and methods of use | GLYSCEND, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-20220396651-A1 | BENZOXABOROLE POLYMERS AND METHODS OF USE | GLYSCEND, INC. | 2022-12-15 | — | — | US | disclosed |
| EP-0285383-A2 | Treatment of prostatic carcinoma with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones | MERCK & CO. INC. (US) | 1988-10-05 | — | — | EP | disclosed |
| EP-0285382-A2 | Treatment of androgenic alopecia with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones | MERCK & CO. INC. (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4760071-A | Enzyme inhibitor | MERCK & CO., INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4558101-A | FROM HYDROCARBON POLYMER CONTAINING OLEFINIC GROUPS WITH HYDROGEN CARBON MONOXIDE AND AMINE USING GROUP 8 METAL CATALYST | W. R. GRACE & CO. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0155096-A2 | 17 Beta-Substituted-4-aza-5-alpha-androstenones and their use as 5-alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1985-09-18 | — | — | EP | disclosed |
| US-4526936-A | Reacting polymeric hydrocarbon, primary or secondary amine, carbon monoxide, hydrogen, in the presence of group VIII metal catalyst | W. R. GRACE & CO. (US) | 1985-07-02 | — | — | US | disclosed |
| US-4312965-A | Process for forming amine/amide containing polymers | W. R. GRACE & CO. (US) | 1982-01-26 | — | — | US | disclosed |
| US-4113764-A | Manufacture of N-substituted glycinonitriles | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4083849-A | Process for preparation of 5-cyanopyrid-6-ones | BASF AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-4022815-A | Manufacture of substituted glycinonitriles | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |