Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554878 | 0.94 | MEN1 (0.55) | HTTMEN1KMT2ATHRBMAPT | |
| SCHEMBL29091228 | 0.91 | HTT (0.52) | HTTMEN1KMT2ATHRBMAPT | |
| SCHEMBL404985 | 0.91 | HTT (0.52) | HTTMEN1KMT2ATHRBMAPT | |
| SCHEMBL10649572 | 0.89 | USP2 (0.65) | HTTMEN1KMT2ATHRBMAPT | |
| SCHEMBL14922021 | 0.87 | USP2 (0.51) | HTTUSP2LPAR1LPAR3LPAR5 | |
| SCHEMBL27804871 | 0.87 | TSHR (0.52) | HTTMEN1KMT2ATHRBMAPT | |
| SCHEMBL1882441 | 0.85 | HTT (0.60) | HTTMEN1KMT2ATHRBMAPT | |
| SCHEMBL5489968 | 0.85 | HTT (0.60) | HTTMEN1KMT2ATHRBMAPT | |
| SCHEMBL10993374 | 0.85 | HTT (0.60) | HTTMEN1KMT2ATHRBMAPT | |
| SCHEMBL18628322 | 0.85 | HTT (0.60) | HTTMEN1KMT2ATHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889953-A | ANTITUMOR AND -CARCINOGENIC AGENTS; PLATELET ACTIVATING FACTOR ANTAGONIST; CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0254540-A2 | Glycerol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |