Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 6/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554151 | 1.00 | MIF (0.55) | MIFCA2CA1KMT2AMEN1 | |
| SCHEMBL10553690 | 0.96 | MIF (0.56) | MIFCA2CA1KMT2AMEN1 | |
| SCHEMBL10553692 | 0.96 | MIF (0.56) | MIFCA2CA1KMT2AMEN1 | |
| SCHEMBL10555517 | 0.95 | MIF (0.57) | MIFCA2CA1KMT2AMEN1 | |
| SCHEMBL12041932 | 0.87 | MIF (0.57) | MIFFAAH | |
| SCHEMBL349916 | 0.85 | MIF (0.58) | MIFCA2CA1FAAH | |
| SCHEMBL349917 | 0.85 | MIF (0.58) | MIFCA2CA1FAAH | |
| SCHEMBL20848265 | 0.85 | MIF (0.44) | MIFCA2KMT2AMEN1NPC1 | |
| SCHEMBL20848254 | 0.84 | MIF (0.57) | MIFKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL20848130 | 0.84 | MIF (0.57) | MIFKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4866206-A | INHIBITORS OF ORNITHINE DECARBOXYLASE | MERRELL DOW FRANCE ET CIE (FR) | 1989-09-12 | — | — | US | disclosed |
| US-4743691-A | INHIBITORS OF ORNITHINE DECARBOXYLASE | MERRELL DOW FRANCE ET CIE (FR) | 1988-05-10 | — | — | US | disclosed |