Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919447 | 0.90 | APP (0.47) | ALDH1A1MAPTRAB9AMAPK14NOTUM | |
| SCHEMBL8797223 | 0.89 | MAPT (0.68) | ALDH1A1MAPTRAB9AMAPK14KDM4E | |
| SCHEMBL4043697 | 0.88 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL14559426 | 0.87 | MAPK14 (0.60) | ALDH1A1MAPTRAB9AMAPK14KDM4E | |
| SCHEMBL13939922 | 0.87 | MAPT (0.69) | ALDH1A1MAPTRAB9AMAPK14KDM4E | |
| SCHEMBL10565418 | 0.83 | AKR1B1 (0.62) | — | |
| SCHEMBL10555531 | 0.80 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL3098370 | 0.79 | MAPK14 (0.68) | ALDH1A1MAPTRAB9AMAPK14KDM4E | |
| SCHEMBL15782103 | 0.78 | MAPK14 (0.52) | MAPK14MAOB | |
| SCHEMBL15766737 | 0.78 | MAPK14 (0.51) | MAPK14TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889858-A | ANTIHYPOXIC AGENTS, ANTICONVULSANTS, LIPID PEROXIDATION INHIBITORS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |