Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.52 |
| ▸ | PIM1 | P11309 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10556029 | 0.88 | CYP19A1 (0.54) | CDC7PIM1GSK3BCSNK2A1MAPK13 | |
| SCHEMBL10551416 | 0.84 | CDK5 (0.41) | CDC7PIM1GSK3BCSNK2A1MAPK13 | |
| SCHEMBL10552179 | 0.76 | KCNH2 (0.47) | CDC7PIM1GSK3BCSNK2A1MAPK13 | |
| SCHEMBL2352218 | 0.76 | AKT1 (0.52) | PIM1GSK3BDAPK3PRKD3MAP4K4 | |
| SCHEMBL2244776 | 0.71 | NPC1 (0.78) | KDM4ECYP19A1NPC1RAB9AALDH1A1 | |
| SCHEMBL9669299 | 0.70 | CDC7 (0.40) | CDC7PIM1GSK3BCSNK2A1MAPK13 | |
| SCHEMBL6508629 | 0.69 | HPGD (0.49) | CDC7PIM1GSK3BCSNK2A1MAPK13 | |
| SCHEMBL12124985 | 0.69 | NPC1 (0.75) | KDM4ECYP19A1NPC1RAB9AALDH1A1 | |
| SCHEMBL4887738 | 0.69 | KDM4E (0.64) | KDM4ECYP19A1NPC1RAB9AALDH1A1 | |
| SCHEMBL385584 | 0.68 | CDC7 (1.00) | CDC7PIM1GSK3BCSNK2A1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851406-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-25 | — | — | US | disclosed |