SCHEMBL1055495

SCHEMBL1055495

NC(=O)[C@@H]1C[C@H](O)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2645734 1.00
SCHEMBL1371626 1.00
SCHEMBL6687479 1.00
SCHEMBL5131181 1.00
SCHEMBL2645580 1.00
SCHEMBL2645578 1.00
SCHEMBL3678625 1.00
SCHEMBL1025829 1.00
Hydrochloric Acid SCHEMBL3974504 0.98 DPP4 (0.42)
Hydrochloric Acid SCHEMBL9834698 0.98 DPP4 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115256-A1 HUMAN AMYLIN ANALOG, AND DERIVATIVE THEREOF AND USE THEREOF HANGZHOU SCIWIND BIOSCIENCES CO., LTD. (CN) 2026-04-30 US disclosed
CN-120130489-A Application of hydroxyproline and derivatives thereof, biological herbicide, broad-spectrum herbicide and weed control method 三亚市国家耐盐碱水稻技术创新中心 2025-06-13 CN disclosed
EP-4534553-A1 HUMAN AMYLIN ANALOG, AND DERIVATIVE AND USE THEREOF Hangzhou Sciwind Biosciences Co., Ltd. (CN) 2025-04-09 EP disclosed
US-9670228-B2 Benzoxazepin PI3K inhibitor compounds and methods of use GENENTECH, INC. (US) 2017-06-06 US disclosed
US-20170081341-A1 BENZOXAZEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2017-03-23 US disclosed
US-9198918-B2 Benzoxazepin PI3K inhibitor compounds and methods of use GENENTECH, INC. (US) 2015-12-01 US disclosed
EP-2845592-A1 Benzoxazepin PI3K inhibitor compounds and methods of use F. Hoffmann-La Roche AG (CH) 2015-03-11 EP disclosed
US-8940771-B2 Organic compounds NOVARTIS AG (CH) 2015-01-27 US disclosed
US-20140288047-A1 BENZOXAZEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2014-09-25 US disclosed
US-8785626-B2 Benzoxazepin PI3K inhibitor compounds and methods of use GENENTECH, INC. (US) 2014-07-22 US disclosed
CN-1882576-A Quinazoline derivatives ASTRAZENECA AB (SE) 2006-12-20 CN disclosed
WO-2006122188-A2 TRIPEPTIDES AS HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2006-11-16 WO disclosed
EP-1664030-A1 QUINAZOLINE DERIVATIVES AstraZeneca AB (SE) 2006-06-07 EP disclosed
WO-2005026156-A1 QUINAZOLINE DERIVATIVES ASTRAZENECA AB (SE) 2005-03-24 WO disclosed
EP-1127889-B1 Chiral molecular magnet and manufacturing method of the same NAT INST NATURAL SCIENCES (JP) 2004-10-20 EP disclosed
US-6355820-B1 MONOCRYSTAL MAGNET POURING SOLUTIONS OF DIAMINE, MANGANATE SALT, DEAERATION SOLVENT, HEXACYANOCHROMATE SALT AND PRECIPITATION OF MANGANESE, HEXACYANO CHROMIUM WITH DIAMINO LIGAND OKAZAKI NATIONAL RESEARCH INSTITUTES (JP) 2002-03-12 US disclosed
EP-1127889-A2 Chiral molecular magnet and manufacturing method of the same Okazaki National Research Institutes (JP) 2001-08-29 EP disclosed
EP-0762887-A4 ACYLATED ENOL DERIVATIVES AS PRODRUGS OF ELASTASE INHIBITORS MERRELL PHARMA INC (US) 1999-03-31 EP disclosed
EP-0762887-A1 ACYLATED ENOL DERIVATIVES AS PRODRUGS OF ELASTASE INHIBITORS MERRELL PHARMACEUTICALS INC. (US) 1997-03-19 EP disclosed
WO-1995033478-A1 ACYLATED ENOL DERIVATIVES AS PRODRUGS OF ELASTASE INHIBITORS MERRELL PHARMACEUTICALS INC. (US) 1995-12-14 WO disclosed