Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558629 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL11118127 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL10557899 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL10559894 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL10554361 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL10559952 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL10557888 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL10554770 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL10554850 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL10555291 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812258-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-03-14 | — | — | US | disclosed |
| EP-0126949-A2 | Fluorine-containing pyrimidine derivatives | MERCK PATENT GmbH (DE) | 1984-12-05 | — | — | EP | disclosed |