Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.41 |
| ▸ | RELA | Q04206 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557201 | 1.00 | RARB (0.57) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10559029 | 1.00 | RARB (0.57) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10559046 | 1.00 | RARB (0.57) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10558305 | 1.00 | RARB (0.57) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10555932 | 1.00 | RARB (0.57) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10557928 | 1.00 | RARB (0.57) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10557032 | 0.99 | RARB (0.58) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10554236 | 0.99 | RARB (0.58) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10558896 | 0.99 | RARB (0.58) | RARBRAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10556001 | 0.99 | RARB (0.58) | RARBRAB9ASMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812258-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-03-14 | — | — | US | disclosed |
| EP-0126949-A2 | Fluorine-containing pyrimidine derivatives | MERCK PATENT GmbH (DE) | 1984-12-05 | — | — | EP | disclosed |