SCHEMBL10556752

SCHEMBL10556752

O=C(c1ccccc1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.64
ALOX15 P16050 1/20 0.64
HTT P42858 1/20 0.64
HBB P68871 1/20 0.64
HDAC3 O15379 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
HDAC9 Q9UKV0 1/20 0.53
HDAC5 Q9UQL6 1/20 0.53
NCOR2 Q9Y618 1/20 0.53
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
EP300 Q09472 1/20 0.46
EPHX1 P07099 2/20 0.42
POLB P06746 1/20 0.42
TSHR P16473 2/20 0.42
DAO P14920 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28074712 0.86 MAPT (0.48) MAPTALOX15HTTHBBHDAC3
SCHEMBL40500 0.79 HDAC3 (0.59) MAPTALOX15HTTHBBHDAC3
SCHEMBL30001332 0.79 HDAC3 (0.59) MAPTALOX15HTTHBBHDAC3
Benzene SCHEMBL28538497 0.79 HDAC3 (0.59) MAPTALOX15HTTHBBHDAC3
SCHEMBL11451081 0.78 MAPT (1.00) MAPTALOX15HTTHBBCYP1A2
SCHEMBL13092132 0.78 MAPT (0.48) MAPTALOX15HTTHBBEP300
SCHEMBL1127769 0.78 ATM (0.61) MAPTALOX15HTTHBBHDAC3
SCHEMBL25255069 0.77 HDAC3 (0.47) MAPTALOX15HTTHBBHDAC3
Hydrochloric Acid SCHEMBL7052205 0.77 HDAC3 (0.57) MAPTALOX15HTTHBBHDAC3
SCHEMBL3404308 0.77 HDAC3 (0.52) MAPTALOX15HTTHBBHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109752326-A A method of using the content of germanium in spectrophotometry measurement sea cucumber 江苏维赛科技生物发展有限公司 2019-05-14 CN disclosed
US-4801722-A FLUORESCENT LABELS EASTMAN KODAK COMPANY (US) 1989-01-31 US disclosed
US-4794191-A FLUORESCENT LABELS EASTMAN KODAK COMPANY (US) 1988-12-27 US disclosed
EP-0068875-B1 FLUORESCENT CHELATES AND LABELED SPECIFIC BINDING REAGENTS PREPARED THEREFROM EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-12-23 EP disclosed
US-4670572-A IMMUNOASSAY EASTMAN KODAK COMPANY (US) 1987-06-02 US disclosed
US-4637988-A BINDING, ADSORPTION LANTHANIDE CHELATE COMPOUNDS EASTMAN KODAK COMPANY (US) 1987-01-20 US disclosed
EP-0068875-A2 Fluorescent chelates and labeled specific binding reagents prepared therefrom EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-05 EP disclosed
US-4052283-A FROM ALLENE AND HYDROGEN SULFIDE, POLYMERIZATION HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-10-04 US disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed
US-3992274-A ALLENE COMPOUNDS, HYDROGEN SULFIDE, PHOTOSENSITIZING AGENT HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-11-16 US disclosed