Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679577 | 0.86 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1LIPGCSNK1EALDH1A1 | |
| SCHEMBL17027717 | 0.85 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1LIPGCSNK1EALDH1A1 | |
| SCHEMBL17027726 | 0.85 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1LIPGCSNK1EALDH1A1 | |
| SCHEMBL17027756 | 0.85 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1LIPGCSNK1EALDH1A1 | |
| SCHEMBL17027746 | 0.85 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1LIPGCSNK1EALDH1A1 | |
| SCHEMBL17027712 | 0.85 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1LIPGCSNK1EALDH1A1 | |
| SCHEMBL17027796 | 0.85 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1LIPGCSNK1EALDH1A1 | |
| SCHEMBL6682255 | 0.84 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1LIPGALDH1A1TSHR | |
| SCHEMBL6684349 | 0.84 | CSNK1E (0.42) | CYSLTR2CYSLTR1CSNK1EALDH1A1TSHR | |
| SCHEMBL6678854 | 0.82 | TSHR (0.43) | CYSLTR2CYSLTR1CSNK1EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883614-A | TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1989-11-28 | — | — | US | disclosed |