Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 8/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | VCP | P55072 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HPRT1 | P00492 | 11/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553712 | 1.00 | PNP (0.60) | PNPBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL9651453 | 0.94 | BLM (0.65) | PNPBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL6377806 | 0.89 | BLM (0.72) | PNPBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL6835438 | 0.89 | PNP (0.61) | PNPBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL6840470 | 0.89 | BLM (0.72) | PNPBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL8981399 | 0.89 | PNP (0.61) | PNPBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL6835357 | 0.89 | BLM (0.72) | PNPBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL6839480 | 0.88 | PNP (0.60) | PNPBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL8446591 | 0.88 | PNP (0.60) | PNPBLMMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6380553 | 0.88 | BLM (0.71) | PNPBLMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880820-A | VIRICIDES, HERPES VIRUS | MERCK & CO., INC. (US) | 1989-11-14 | — | — | US | claimed |
| EP-0130126-A1 | (S)-9-(2,3-dihydroxy-1-propoxymethyl) guanine and its acyl derivatives, their preparation and their application as antiherpetic agents | MERCK & CO. INC. (US) | 1985-01-02 | — | — | EP | claimed |
| US-4880820-A | VIRICIDES, HERPES VIRUS | MERCK & CO., INC. (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0130126-B1 | (S)-9-(2,3-DIHYDROXY-1-PROPOXYMETHYL) GUANINE AND ITS ACYL DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTIHERPETIC AGENTS | MERCK & CO. INC. (US) | 1987-08-26 | — | — | EP | disclosed |