Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566155 | 0.83 | DRD3 (0.60) | DRD3DRD2DRD4DRD1NPC1 | |
| SCHEMBL23964195 | 0.79 | DRD3 (0.60) | DRD3DRD2DRD4DRD1LMNA | |
| Maleic Acid SCHEMBL27373430 | 0.78 | DRD3 (0.49) | DRD3DRD2DRD4DRD1HTR1A | |
| Formic Acid SCHEMBL23932580 | 0.76 | DRD3 (0.54) | DRD3DRD2DRD4DRD1LMNA | |
| SCHEMBL23932533 | 0.74 | MAPK1 (0.45) | DRD3DRD2DRD4DRD1LMNA | |
| SCHEMBL23964126 | 0.74 | DRD3 (0.51) | DRD3DRD2DRD4DRD1TP53 | |
| SCHEMBL30041262 | 0.74 | MAPK1 (0.46) | DRD3DRD2DRD4DRD1LMNA | |
| SCHEMBL23932495 | 0.74 | MAPK1 (0.46) | DRD3DRD2DRD4DRD1LMNA | |
| SCHEMBL23964258 | 0.73 | DRD3 (0.50) | DRD3DRD2DRD4DRD1TP53 | |
| SCHEMBL5633385 | 0.73 | NPC1 (0.54) | DRD3DRD2DRD4DRD1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877878-A | 2-azolylmethyl-2-aryl-1,3-dioxolanes and the salts thereof, processes for the preparation thereof, agents containing same, and the use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
| US-4818758-A | FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0237964-A2 | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and their salts, processes for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |