Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 6/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GLB1 | P16278 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279547 | 0.82 | GBA1 (0.43) | FUCA1GLAGBA1PYGLGBA2 | |
| SCHEMBL3278572 | 0.82 | GBA1 (0.43) | FUCA1GLAGBA1PYGLGBA2 | |
| SCHEMBL3279555 | 0.82 | GBA1 (0.43) | FUCA1GLAGBA1PYGLGBA2 | |
| SCHEMBL3233892 | 0.82 | GBA1 (0.43) | FUCA1GLAGBA1PYGLGBA2 | |
| SCHEMBL3278567 | 0.82 | GBA1 (0.43) | FUCA1GLAGBA1PYGLGBA2 | |
| SCHEMBL17249606 | 0.79 | — | — | |
| SCHEMBL10513002 | 0.78 | FUCA1 (0.42) | FUCA1GLASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10512633 | 0.78 | FUCA1 (0.42) | FUCA1GLASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10513518 | 0.78 | FUCA1 (0.42) | FUCA1GLASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10512642 | 0.78 | FUCA1 (0.42) | FUCA1GLASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4864023-A | MICROBIOCIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4801584-A | ANTIMICROBIAL | HOFFMANN-LA ROCHE INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0259804-A2 | Pyrido[3,2,1-ij]-1,3,4-benzoxadiazine derivatives, process for their preparation, resulting pharmaceutical preparations and intermediates for use in the process | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-16 | — | — | EP | disclosed |