Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CCKBR | P32239 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674145 | 1.00 | MEN1 (0.53) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL11773759 | 0.92 | MEN1 (0.47) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL11734468 | 0.89 | KMT2A (0.46) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL11011053 | 0.89 | KMT2A (0.45) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL10751872 | 0.89 | MEN1 (0.52) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL11218597 | 0.89 | MEN1 (0.52) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL11218592 | 0.89 | MEN1 (0.52) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL11684557 | 0.88 | KMT2A (0.46) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL11685395 | 0.88 | MEN1 (0.44) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL11691218 | 0.87 | MEN1 (0.44) | MEN1KMT2ACCKBRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801704-A | PENICILLINS | HOFFMAN-LA ROCHE INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0206000-A1 | (2,3)-Alpha-methylenepenam-3-carboxylic acids and derivatives thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1986-12-30 | — | — | EP | disclosed |
| US-4556516-A | Process for the preparation of acylureido penicillin derivatives | BORYUNG PHARMACEUTICAL CO., LTD. (KR) | 1985-12-03 | — | — | US | disclosed |
| US-4016282-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3980792-A | EFFECTIVE AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE INFECTIONS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |
| US-3978223-A | UREIDOACETAMIDO-PENICILLINS FOR TREATING BACTERIAL INFECTIONS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |
| US-3974140-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3959258-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |
| US-3939149-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |
| US-3936442-A | ANTIBIOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |
| US-3933795-A | Ureidoacetamido-penicillins | Konig, Hans-Bodo (DT) | 1976-01-20 | — | — | US | disclosed |