Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | THPO | P40225 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.59 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564553 | 0.95 | NR3C2 (0.67) | NR3C2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10746223 | 0.87 | CYP1A2 (0.70) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10686790 | 0.87 | CYP1A2 (0.70) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10681742 | 0.87 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10721453 | 0.87 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10566134 | 0.87 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7564216 | 0.86 | NR3C2 (0.69) | NR3C2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10677047 | 0.85 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10683469 | 0.85 | MEN1 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10684790 | 0.84 | MEN1 (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818766-A | ANTIARRHYTHMIA AGENTS, HYPOTENSIVE AGENTS, TREATMENT OF ANGINA | CIBA-GEIGY CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |