SCHEMBL10565634

SCHEMBL10565634

ClC/C=C/COc1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.42
MAOB P27338 4/20 0.40
APP P05067 1/20 0.40
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
SCN4A P35499 2/20 0.37
KCNH2 Q12809 1/20 0.37
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9658000 1.00 AOC3 (0.42) AOC3MAOBAPPCYP1A2CYP2C9
SCHEMBL11229991 0.82 MAOB (0.57) AOC3MAOBAPPSCN4A
SCHEMBL7403066 0.81 AOC3 (0.64) AOC3MAOBCYP2C9CYP2C19KCNH2
SCHEMBL7403068 0.81 AOC3 (0.64) AOC3MAOBCYP2C9CYP2C19KCNH2
SCHEMBL11101055 0.79 MAOB (0.40) AOC3MAOBAPPCYP1A2CYP2C9
SCHEMBL10348527 0.79 MAOB (0.40) AOC3MAOBAPPCYP1A2CYP2C9
SCHEMBL10905751 0.79 MAOB (0.40) AOC3MAOBAPPCYP1A2CYP2C9
SCHEMBL11101052 0.79 MAOB (0.40) AOC3MAOBAPPCYP1A2CYP2C9
SCHEMBL1714415 0.79 MAOB (0.44) AOC3MAOB
SCHEMBL1714419 0.79 MAOB (0.44) AOC3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4797409-A FUNGICIDES, YEAST INFECTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-10 US disclosed