Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13128175 | 1.00 | SRC (0.47) | SRCAHRL3MBTL1TSHRCHRM5 | |
| SCHEMBL10567381 | 1.00 | SRC (0.47) | SRCAHRL3MBTL1TSHRCHRM5 | |
| SCHEMBL12756972 | 0.79 | CHRM5 (0.62) | SRCCHRM5ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL16395504 | 0.79 | SRC (0.42) | SRCAHRL3MBTL1CHRM5KDM4E | |
| SCHEMBL16395502 | 0.79 | SRC (0.42) | SRCAHRL3MBTL1CHRM5KDM4E | |
| SCHEMBL12756974 | 0.77 | MAOB (0.52) | SRCL3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL14480023 | 0.77 | MAOB (0.52) | SRCL3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL14572064 | 0.74 | SRC (0.48) | SRCL3MBTL1TSHRCHRM5KDM4E | |
| SCHEMBL13128174 | 0.73 | CYP1B1 (0.56) | SRCAHRCHRM5KDM4EALDH1A1 | |
| SCHEMBL13128152 | 0.73 | SRC (0.47) | SRCCHRM5ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810811-A | CHEMICAL INTERMEDIATES | SMITHKLINE BECKMAN CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4707488-A | HYPOTENSIVE AGENTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |