Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | TYMS | P04818 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26017824 | 0.76 | HPGD (0.53) | HPGDALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL3425926 | 0.76 | HPGD (0.53) | HPGDALDH1A1TSHRMEN1MAPK1 | |
| SCHEMBL3122203 | 0.76 | PARP1 (0.59) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15599438 | 0.76 | HPGD (0.53) | HPGDALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL14637875 | 0.76 | PARP1 (0.50) | HPGDALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL22424240 | 0.76 | TYMS (0.41) | TYMSMEN1KMT2ATNKS2PARP1 | |
| SCHEMBL14638235 | 0.74 | HPGD (0.51) | HPGDALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL17011678 | 0.74 | TNKS2 (0.54) | TYMSTNKSTNKS2WNT3A | |
| SCHEMBL18689727 | 0.72 | HPGD (0.50) | HPGDALDH1A1TSHRMEN1MAPK1 | |
| SCHEMBL18703579 | 0.72 | HPGD (0.49) | HPGDALDH1A1TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123750-A1 | Condensed amino pyrimidinones and their use in the treatment and prophylaxis of viral infections | BIOMEASURE, INC. (US) | 1984-11-07 | — | — | EP | claimed |
| US-4814335-A | Antiviral compounds | BIOMEASURE, INCORPORATED (US) | 1989-03-21 | — | — | US | disclosed |
| US-4625026-A | 2-amino-4-oxo-tricyclicpyrimidines having antiviral activities against herpes simplex virus type II infections | BIOMEASURE, INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0123750-A1 | Condensed amino pyrimidinones and their use in the treatment and prophylaxis of viral infections | BIOMEASURE, INC. (US) | 1984-11-07 | — | — | EP | disclosed |