Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461182 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10573110 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9461799 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10763997 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10874090 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10550996 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10569885 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10570723 | 0.83 | TOP2A (0.53) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10563642 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL2738965 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847375-A | Antibacterial 1,8-bridged 4-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-11 | — | — | US | disclosed |