Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10696287 | 0.98 | CHRM1 (0.43) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL10569051 | 0.88 | CHRM1 (0.47) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL12857420 | 0.87 | CHRM1 (0.37) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL10572336 | 0.85 | CHRM1 (0.45) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL10567484 | 0.84 | CHRM1 (0.44) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| Oxalic Acid SCHEMBL10569543 | 0.82 | CHRM1 (0.51) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9094744 | 0.78 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL12017242 | 0.78 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL13300984 | 0.78 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL12674256 | 0.76 | CHRM1 (0.43) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870081-A | DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1989-09-26 | — | — | US | claimed |
| EP-0257741-A2 | Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-03-02 | — | — | EP | claimed |
| US-4870081-A | DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1989-09-26 | — | — | US | disclosed |
| EP-0257741-A2 | Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-03-02 | — | — | EP | disclosed |