Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 9/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.69 |
| ▸ | DRD3 | P35462 | 3/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.69 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.69 |
| ▸ | HTR1A | P08908 | 2/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.69 |
| ▸ | DRD1 | P21728 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.69 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.69 |
| ▸ | HTR2B | P41595 | 2/20 | 0.69 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569551 | 1.00 | CACNA1C (0.69) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| Fumaric Acid SCHEMBL9760768 | 0.95 | CACNA1C (0.63) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| Fumaric Acid SCHEMBL9760752 | 0.95 | CACNA1C (0.63) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| Olradipine SCHEMBL9760691 | 0.91 | TBXA2R (0.83) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| Olradipine SCHEMBL30295459 | 0.91 | TBXA2R (0.83) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| Olradipine SCHEMBL9760698 | 0.91 | TBXA2R (0.83) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| Olradipine SCHEMBL1344914 | 0.91 | TBXA2R (0.83) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| Olradipine SCHEMBL1228947 | 0.91 | TBXA2R (0.81) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| Olradipine SCHEMBL29597339 | 0.91 | TBXA2R (0.81) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 | |
| SCHEMBL9760878 | 0.90 | TBXA2R (0.66) | CACNA1CADRA1AABCB11TBXA2RSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870091-A | CALCIUM CHANNEL BLOCKERS | ADIR ET CIE (FR) | 1989-09-26 | — | — | US | claimed |