Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10569361 | 0.97 | POLB (0.48) | POLBHSD17B10ALDH1A1KDM4ESTAT3 | |
| Oxalic Acid SCHEMBL10574298 | 0.95 | POLB (0.49) | POLBHSD17B10ALDH1A1KDM4ESTAT3 | |
| SCHEMBL10652857 | 0.95 | POLB (0.51) | POLBHSD17B10ALDH1A1KDM4ESTAT3 | |
| Oxalic Acid SCHEMBL10573991 | 0.86 | POLB (0.48) | POLBHSD17B10ALDH1A1KDM4ESTAT3 | |
| Oxalic Acid SCHEMBL10573320 | 0.85 | POLB (0.48) | POLBHSD17B10ALDH1A1KDM4ESTAT3 | |
| Oxalic Acid SCHEMBL10573986 | 0.84 | POLB (0.47) | POLBHSD17B10ALDH1A1KDM4ESTAT3 | |
| SCHEMBL10570434 | 0.83 | POLB (0.50) | POLBHSD17B10ALDH1A1STAT3LMNA | |
| Hydrochloric Acid SCHEMBL10572689 | 0.83 | POLB (0.55) | POLBHSD17B10ALDH1A1STAT3LMNA | |
| Nicainoprol SCHEMBL1816282 | 0.83 | HSD17B10 (0.49) | POLBHSD17B10ALDH1A1STAT3LMNA | |
| SCHEMBL10573458 | 0.82 | POLB (0.51) | POLBHSD17B10ALDH1A1KDM4ESTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845099-A | ANTIARRHYTHMIA AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |