Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046528 | 0.90 | SRD5A2 (0.49) | HCAR2SMN1; SMN2RAB9ASRD5A2 | |
| SCHEMBL7447435 | 0.75 | SLC18A3 (0.58) | HCAR2SMN1; SMN2SLC18A3KDM4EGAA | |
| SCHEMBL30503707 | 0.75 | HCAR2 (0.43) | HCAR2SMN1; SMN2HRH3BCAT2ABL1 | |
| SCHEMBL26917212 | 0.74 | HCAR2 (0.58) | HCAR2HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL16913974 | 0.74 | POLB (0.58) | HCAR2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL31703845 | 0.74 | HCAR2 (0.58) | HCAR2HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL6494263 | 0.73 | KDM4E (0.58) | HTR2AHTR2CHTR2BNPC1RAB9A | |
| SCHEMBL25408158 | 0.72 | HCAR2 (0.41) | HCAR2SMN1; SMN2ABL1 | |
| SCHEMBL25407713 | 0.72 | HCAR2 (0.41) | HCAR2SMN1; SMN2ABL1 | |
| SCHEMBL9949154 | 0.70 | HTR2A (0.36) | HTR2AHTR2CHTR2BSMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4875922-A | FUNGICIDES; PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-10-24 | — | — | US | disclosed |
| CN-87108356-A | PYRIMIDINE DERIVATIVES | — | 1988-09-07 | — | — | CN | disclosed |
| EP-0272813-A2 | Pyrimidine derivatives | ZENECA LIMITED (GB) | 1988-06-29 | — | — | EP | disclosed |