Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.55 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.53 |
| ▸ | POLB | P06746 | 8/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | RECQL | P46063 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576232 | 1.00 | MAPT (0.55) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL16080106 | 0.78 | MAPT (0.62) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL10578612 | 0.74 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL10578610 | 0.74 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL16080104 | 0.71 | MAPT (1.00) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7599877 | 0.71 | MAPT (1.00) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7599882 | 0.71 | MAPT (1.00) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL10575626 | 0.70 | MAPT (0.59) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL10575636 | 0.70 | MAPT (0.59) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL1753097 | 0.69 | MAPT (0.73) | MAPTMEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808599-A | IMMUNOMODULATORY, CARDIOTONIC AGENTS | RHONE-POULENC SANTE (FR) | 1989-02-28 | — | — | US | disclosed |