Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954807 | 0.82 | PDPK1 (0.46) | CASP6PDPK1RAB9ALOXL2CYP2A6 | |
| SCHEMBL29658188 | 0.82 | PDPK1 (0.53) | CASP6PDPK1RAB9ALOXL2CYP2A6 | |
| SCHEMBL23297 | 0.82 | PDPK1 (0.53) | CASP6PDPK1RAB9ALOXL2CYP2A6 | |
| SCHEMBL5945842 | 0.80 | PDPK1 (0.52) | CASP6PDPK1RAB9ALOXL2CYP2A6 | |
| SCHEMBL6067988 | 0.80 | PDPK1 (0.50) | CASP6PDPK1RAB9ALOXL2CYP2A6 | |
| SCHEMBL14862855 | 0.79 | HSP90AA1 (0.45) | CASP6PDPK1RAB9ALOXL2CYP2A6 | |
| Bromide SCHEMBL2363116 | 0.78 | HSP90AA1 (0.44) | CASP6PDPK1RAB9ALOXL2CYP2A6 | |
| SCHEMBL27669186 | 0.77 | PDPK1 (0.48) | CASP6PDPK1RAB9ACYP2A6HSP90AA1 | |
| SCHEMBL26259560 | 0.75 | PDPK1 (0.54) | PDPK1RAB9ALOXL2CYP2A6HSP90AA1 | |
| SCHEMBL5692672 | 0.75 | PDPK1 (0.64) | CASP6PDPK1RAB9ALOXL2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4865641-A | Herbicidal new thiazolyl ether and thioether derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-12 | — | — | US | disclosed |
| EP-0281907-A1 | Thiazolyl ether and thioether derivatives | BAYER AG (DE) | 1988-09-14 | — | — | EP | disclosed |