Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577784 | 1.00 | OPRL1 (0.36) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10582854 | 0.92 | KMT2A (0.36) | OPRL1CYP2C9LMNAMAPTMEN1 | |
| SCHEMBL10582849 | 0.92 | KMT2A (0.36) | OPRL1CYP2C9LMNAMAPTMEN1 | |
| SCHEMBL10582391 | 0.90 | MEN1 (0.38) | OPRL1CYP2C9MAPTMEN1MAPK1 | |
| SCHEMBL10582396 | 0.90 | MEN1 (0.38) | OPRL1CYP2C9MAPTMEN1MAPK1 | |
| SCHEMBL10579337 | 0.90 | OPRL1 (0.35) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10579333 | 0.90 | OPRL1 (0.35) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10582169 | 0.89 | MAPT (0.38) | OPRL1CYP2C9MAPTMEN1MAPK1 | |
| SCHEMBL10582174 | 0.89 | MAPT (0.38) | OPRL1CYP2C9MAPTMEN1MAPK1 | |
| SCHEMBL10582082 | 0.89 | HRH3 (0.34) | OPRL1CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882082-A | PYRIMIDINE DERIVATIVE LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-11-21 | — | — | US | disclosed |
| US-4752414-A | LIQUID CRYSTAL PHASES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-06-21 | — | — | US | disclosed |