SCHEMBL10578317

SCHEMBL10578317

CC(CBr)C(=O)N(CC(=O)OC(C)(C)C)C1CCCC1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10579898 0.86
SCHEMBL11282770 0.86 DPP4 (0.36) DPP4
SCHEMBL7296069 0.83 DPP4 (0.42) DPP4
SCHEMBL10739578 0.82
SCHEMBL11367586 0.81
SCHEMBL11374175 0.81
SCHEMBL11372444 0.81
SCHEMBL10579143 0.80 DPP4 (0.38) DPP4
SCHEMBL20187562 0.80 MEN1 (0.33) DPP4
SCHEMBL10578493 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4839367-A Antihypertensive amide compounds RORER PHARMACEUTICAL CORPORATION (US) 1989-06-13 US disclosed
US-4619944-A AMIDES USV PHARMACEUTICAL CORPORATION (US) 1986-10-28 US disclosed
US-4507316-A Antihypertensive compounds USV PHARMACEUTICAL CORPORATION (US) 1985-03-26 US disclosed
EP-0066254-A1 Mercapto amino acids, process for their preparation and pharmaceutical compositions containing them USV PHARMACEUTICAL CORPORATION (US) 1982-12-08 EP disclosed