Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576253 | 1.00 | SPHK1 (0.40) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10577297 | 1.00 | SPHK1 (0.40) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10579239 | 1.00 | SPHK1 (0.40) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10577302 | 1.00 | SPHK1 (0.40) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10576248 | 1.00 | SPHK1 (0.40) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10582860 | 0.99 | SPHK1 (0.38) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10582862 | 0.99 | SPHK1 (0.38) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10341000 | 0.96 | SPHK1 (0.42) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10340998 | 0.96 | SPHK1 (0.42) | SPHK1RARBMAPTNPC1STAT3 | |
| SCHEMBL10579635 | 0.94 | OPRL1 (0.36) | SPHK1RARBMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882082-A | PYRIMIDINE DERIVATIVE LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-11-21 | — | — | US | disclosed |
| US-4752414-A | LIQUID CRYSTAL PHASES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-06-21 | — | — | US | disclosed |