Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580329 | 1.00 | KMT2A (0.37) | KMT2AMEN1GAAMAPK1MAPT | |
| SCHEMBL10578646 | 0.96 | MEN1 (0.39) | KMT2AMEN1GAAMAPK1MAPT | |
| SCHEMBL10578642 | 0.96 | MEN1 (0.39) | KMT2AMEN1GAAMAPK1MAPT | |
| SCHEMBL10580835 | 0.94 | MAPT (0.39) | KMT2AMEN1GAAMAPK1MAPT | |
| SCHEMBL10580832 | 0.94 | MAPT (0.39) | KMT2AMEN1GAAMAPK1MAPT | |
| SCHEMBL10578378 | 0.91 | OPRL1 (0.36) | KMT2AMEN1MAPK1MAPTCYP2C9 | |
| SCHEMBL10578389 | 0.91 | OPRL1 (0.36) | KMT2AMEN1MAPK1MAPTCYP2C9 | |
| SCHEMBL10582849 | 0.87 | KMT2A (0.36) | KMT2AMEN1GAAMAPK1MAPT | |
| SCHEMBL10581900 | 0.87 | HRH3 (0.36) | KMT2AMEN1GAAMAPK1MAPT | |
| SCHEMBL10581903 | 0.87 | HRH3 (0.36) | KMT2AMEN1GAAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882082-A | PYRIMIDINE DERIVATIVE LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-11-21 | — | — | US | disclosed |
| US-4752414-A | LIQUID CRYSTAL PHASES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-06-21 | — | — | US | disclosed |