Acetamide

Acetamide

SCHEMBL1058244

CC(N)=O.CC(N)=O.NCCCN

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.57
BLM P54132 5/20 0.57
ALOX15 P16050 2/20 0.57
PMP22 Q01453 1/20 0.57
PAOX Q6QHF9 4/20 0.52
CYP1A2 P05177 3/20 0.45
TSHR P16473 3/20 0.45
THRB P10828 2/20 0.45
KMT2A Q03164 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
GABBR2 O75899 2/20 0.45
GABBR1 Q9UBS5 2/20 0.45
GABRR3 A8MPY1 1/20 0.45
GABRP O00591 1/20 0.45
GABRD O14764 1/20 0.45
HDAC3 O15379 1/20 0.45
GABRA1 P14867 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRG2 P18507 1/20 0.45
GABRR1 P24046 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL1060168 1.00
Acetamide SCHEMBL1059742 0.97 BLM (0.53) LMNABLMALOX15PMP22PAOX
Acetamide SCHEMBL6535247 0.90 PAOX (0.65) LMNABLMALOX15PMP22PAOX
Diaminooctane SCHEMBL7801153 0.90 PAOX (0.65) LMNABLMALOX15PMP22PAOX
Acetamide SCHEMBL11158143 0.90 PAOX (0.65) LMNABLMALOX15PMP22PAOX
Acetone SCHEMBL28968430 0.89
Acetic Acid SCHEMBL4397846 0.86 CYP1A2 (0.53) LMNABLMALOX15PAOXCYP1A2
Acetic Acid SCHEMBL9807766 0.86 CYP1A2 (0.53) LMNABLMALOX15PAOXCYP1A2
Acetic Acid SCHEMBL301894 0.86
Acetic Acid SCHEMBL707699 0.86 CYP1A2 (0.53) LMNABLMALOX15PAOXCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8258341-B2 Polyfluorosulfonamido amine and intermediate E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-09-04 US disclosed
US-20110009668-A1 POLYFLUOROSULFONAMIDO AMINE AND INTERMEDIATE E.I. DU POND DE NEMOURS AND COMPANY (US) 2011-01-13 US disclosed